Image:Trypsin vs trypsinogen.png

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[edit] Summary

Description

Trypsinogen (left) vs. Trypsin with trypsin inhibitor (right).

On the left: Trypsinogen (2ptc) with an extra piece of protein (green, only two amino acids are seen).

On the right: After clipping it off by the enteropeptidase in the intestine, the new end of the chain (purple) tucks into the folded Trypsin protein (1tgs) and stabilize the active form of the enzyme. As extra insurance, the pancreas also makes a small protein, trypsin inhibitor (red), that binds to any traces of active trypsin that might be present before it is secreted into the intestine. It binds to the active site of trypsin, blocking its action but not itself being cut into tiny pieces.

(more details...)

Source

Molecule of the Month by www.pdb.org (see the Molecule of the Month section for more details)

Date

Year 2003 (see the complete list for more details)

Author

Illustration by David S. Goodsell of The Scripps Research Institute (see this site)

Permission
(Reusing this image)

Original work of the US Federal Government - public domain


[edit] Licensing

Public domain This work is in the public domain in the United States because it is a work of the United States Federal Government under the terms of Title 17, Chapter 1, Section 105 of the US Code. See Copyright.

Note: This only applies to works of the Federal Government and not to the work of any individual U.S. state, territory, commonwealth, county, municipality, or any other subdivision.


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actuel16 juillet 2006 à 21:37640×385 (52 Kio)Giac83 ({{Information| |Description=Trypsin (1tgs) vs trypsinogen (2ptc) [http://www.pdb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb46_1.html more details...] |Source=''Molecule of the Month'' by ''www.pdb.org'' (see the ''Molecule of the M)

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