Image:Purine Nucleoside Phosphorylase.jpg

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Description
English: Computer-generated Model of Purine Nucleoside Phosphorylase (PNP)
Purine Nucleoside Phosphorylase (PNP) is an important target enzyme for the design of anti-cancer and immunosuppressive drugs. Bacterial PNP, which is slightly different from the human enzyme, is used to synthesize chemotherapeutic agents. Knowledge of the three-dimensional structure of the bacterial PNP molecule is useful in efforts to engineer different types of PNP enzymes, that can be used to produce new chemotherapeutic agents. This picture shows a computer model of bacterial PNP, which looks a lot like a display of colorful ribbons. Principal Investigator was Charles Bugg.
Français : Modèle informatique de la Purine Nucléoside Phosphorylase (PNP)
La PNP est une cible importante pour des molécules actives anticancéreuses ou immunosuppressives. La PNP bactérienne, qui est légèrement différente de l'enzyme humaine, est utilisée pour synthétiser des agents chémothérapeutiques. La connaissance de la structure tridimensionnelle de la PNP bactérienne est utile pour obtenir différentes sortes d'enzymes PNP, pouvant être utilisées pour produire de nouveaux agents chémothérapeutiques. Cette image a été réalisée par une équipe dirigée par Charles Bugg.
Source

Science Directorate at Marshall Space Flight Center (MSFC) (NASA), MSFC Negative Number: 8772406, Reference Number: P-2757

Date

released 1. Feb. 1987

Author

NASA

Permission
(Reusing this image)

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Public domain
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Picture of the day This image was selected as a picture of the day for February 6, 2005. It was captioned as followed:
English: Computer-generated Model of Purine Nucleoside Phosphorylase (PNP)

Български: Компютърно генериран модел на пурин-нуклеозидна фосфорилаза (PNP)
Česky: Počítačem vytvořený model purinnukleosidfosforylázy (PNP)
Deutsch: Ein Model eines computergenerierten Purine Nucleoside Phosphorylase-Enzyms (PNP)
English: Computer-generated Model of Purine Nucleoside Phosphorylase (PNP)
Esperanto: Komputile generita Modelo de Purine Nucleoside Phosphorylase (PNP)
Español: Modelo originado en ordenador del phosphorylase del nucleoside del purine (PNP)
Français : Modélisation informatique d'une Purine Nucléoside Phosphorylase (enzyme)
Magyar: A "Purin nukleozid foszforiláz" (PNP) számítógéppel generált modellje
Italiano: Modello generato al computer della Purine Nucleoside Phosphorylase (PNP)
日本語: コンピュータで作製されたプリン・ヌクレオシド・ホスホリラーゼ(PNP)のモデル
Lëtzebuergesch : Computergeneréierte Modell vun engem Purine Nucleoside Phosphorylase (PNP) (Enzym).
Nederlands: Computermodel van Purine Nucleoside Phosphorylase (PNP)
Polski: Wygenerowany komputerowo model enzymu PNP.
Português: Modelo gerado por computador de uma Purine Nucleoside Phosphorylase (PNP)
Română: Model generat pe Calculator al PNP ( Purine Nucleoside Phophorylase )
Русский: Компьютерная модель Purine Nucleoside Phosphorylase (PNP)
‪中文(简体)‬: 计算机模拟细菌的嘌呤核苷磷酸化酶的三维结构图

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